| Gene Information | |
|---|---|
| Gene Name | CPSF3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 684 |
| Protein Names | Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000119203 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9UKF6 |
| Gene Card | CPSF3 |
| Uniprot ID | Q9UKF6 |
| Pfam | PF10996; PF11718; PF00753; PF07521 |
| In ASD | no |
| Allosteric Prediction | no (-0.497355656) |
| Ortholog in Animals | Alpaca_ CPSF3 ( ortholog_one2one ) Dog_ CPSF3 ( ortholog_one2one ) GuineaPig_ CPSF3 ( ortholog_one2one ) Macaque_ CPSF3 ( ortholog_one2one ) Mouse_ Cpsf3 ( ortholog_one2one ) Pig_ CPSF3 ( ortholog_one2one ) Rat_ Cpsf3 ( ortholog_one2one ) Rabbit_ CPSF3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | INTS11, CPSF2, INTS9 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2I7T (X-ray 2.10A ) 2I7V (X-ray 2.10A ) 6M8Q (X-ray 2.49A ) 6V4X (EM 3.20A ) |
| DBSNP | rs17850770 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15037765}. |
| Mouse PG classification | NA |
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