| Gene Information | |
|---|---|
| Gene Name | DAZAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 407 |
| Protein Names | DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000071626 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96EP5 |
| Gene Card | DAZAP1 |
| Uniprot ID | Q96EP5 |
| Pfam | PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-1.375217897) |
| Ortholog in Animals | Alpaca_ DAZAP1 ( ortholog_one2one ) Dog_ DAZAP1 ( ortholog_one2one ) GuineaPig_ DAZAP1 ( ortholog_one2one ) Macaque_ DAZAP1 ( ortholog_one2one ) Mouse_ Dazap1 ( ortholog_one2one ) Pig_ DAZAP1 ( ortholog_one2one ) Rat_ Dazap1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | RBM46, RBM19, MSI2, HNRNPA1L2, HNRNPA1L3, HNRNPA1, A1CF, RBM39, RBM23, TIAL1, RBMX, RBMXL1, HNRNPA0, HNRNPAB, CIRBP, RBM3, HNRNPA3, RBMY1D, RBMY1B, RBMY1A1, RBMY1J, RBMY1F, RBMY1E, MSI1, RBM47, TRNAU1AP, HNRNPA2B1, RBMXL2, RBMXL3, RBM4, RBM4B, HNRNPD, DND1, NCL, HNRNPDL, TIA1 |
| Tissue | NA |
| Tissue Specificity | Mainly expressed in testis. Expressed to a lower level in thymus. Weakly or not expressed in heart, liver, brain, placenta, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10857750}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2DGS (NMR - ) 2DH8 (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:22001406}. Nucleus {ECO:0000269|PubMed:22001406}. Note=Predominantly cytoplasmic (By similarity). Nuclear at some stages of spermatozoides development. In midpachytene spermatocytes, it is localized in both the cytoplasm and the nuclei and is clearly excluded from the sex vesicles. In round spermatids, it localizes mainly in the nuclei, whereas in elongated spermatids, it localizes to the cytoplasm (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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