| Gene Information | |
|---|---|
| Gene Name | ADM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 148 |
| Protein Names | Protein ADM2 (Intermedin) [Cleaved into: Adrenomedullin-2 (AM2) (Intermedin-long) (IMDL); Intermedin-short (IMDS)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000128165 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q7Z4H4 |
| Gene Card | ADM2 |
| Uniprot ID | Q7Z4H4 |
| Pfam | PF00214 |
| In ASD | no |
| Allosteric Prediction | no (-0.364373041) |
| Ortholog in Animals | Alpaca_ ADM2 ( ortholog_one2one ) Dog_ ADM2 ( ortholog_one2one ) Macaque_ ADM2 ( ortholog_one2one ) Mouse_ Adm2 ( ortholog_one2one ) Pig_ ADM2 ( ortholog_one2one ) Rat_ Adm2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ADM |
| Tissue | kidney, thyroid, pancreas, parotid.gland |
| Tissue Specificity | Expressed in the esophagus, stomach, jejunum, ileum, ileocecum, ascending colon, transverse colon, descending colon and rectum. Expressed in myocardial cells of the heart, renal tubular cells, hypothalamus, and pituitary. {ECO:0000269|PubMed:14615490, ECO:0000269|PubMed:16359754}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6D1U (X-ray 2.05A ) 6UVA (EM 2.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
| click here to return to the previous page | |