| Gene Information | |
|---|---|
| Gene Name | WHAMM |
| Organism | Homo sapiens (Human) |
| Gene Length | 809 |
| Protein Names | WASP homolog-associated protein with actin, membranes and microtubules (WAS protein homology region 2 domain-containing protein 1) (WH2 domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000156232 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8TF30 |
| Gene Card | WHAMM |
| Uniprot ID | Q8TF30 |
| Pfam | PF15871; PF15920 |
| In ASD | no |
| Allosteric Prediction | no (-1.236937969) |
| Ortholog in Animals | Alpaca_ WHAMM ( ortholog_one2one ) Dog_ WHAMM ( ortholog_one2one ) Macaque_ WHAMM ( ortholog_one2one ) Mouse_ Whamm ( ortholog_one2one ) Pig_ WHAMM ( ortholog_one2one ) Rat_ Whamm ( ortholog_one2one ) Rabbit_ WHAMM ( ortholog_one2one ) |
| Ohnologs | JMY |
| Paralogs | JMY, PRR11 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, lung, heart, colon and kidney (at protein level). |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5X1G (EM 4.50A ) |
| DBSNP | rs35270670 rs1055666 rs1055667 rs3814281 rs11259953 rs11259954 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18614018}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000269|PubMed:18614018}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:18614018}. Golgi apparatus, cis-Golgi network {ECO:0000269|PubMed:18614018}. Note=Localized to a perinuclear compartment near the microtubule-organizing center (MTOC). Also detected on tubulo-vesicular structures in the cell periphery that frequently localized along microtubules. {ECO:0000269|PubMed:18614018}. |
| Mouse PG classification | NA |
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