| Gene Information | |
|---|---|
| Gene Name | MLL4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 5537 |
| Protein Names | Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | NA |
| Gene Card | KMT2D |
| Uniprot ID | O14686 |
| Pfam | PF05965; PF05964; PF00628; PF00856 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in most adult tissues, including a variety of hematoipoietic cells, with the exception of the liver. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.01(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3UVK (X-ray 1.40A ) 4ERQ (X-ray 1.91A ) 4Z4P (X-ray 2.20A ) 6O7G (NMR - ) |
| DBSNP | rs200245957 rs1064210 rs776242478 rs200088180 rs202076833 rs75226229 rs1341612248 rs202217665 rs1592145879 rs111266743 rs3741626 rs570260017 rs189888707 rs147706410 rs763347763 rs75937132 rs146044282 rs1342235871 rs80132640 rs778418522 rs533214351 rs375999143 rs1555185875 rs398123724 rs886041404 rs886043497 rs267607237 rs1555185701 rs1942587772 rs398123728 rs398123729 rs3782356 rs1565756106 rs1555185217 rs1565753611 rs267607238 rs1388523736 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:23508102}. |
| Mouse PG classification | NA |
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