Gene Information
Gene NameMLH3
OrganismHomo sapiens (Human)
Gene Length1453
Protein NamesDNA mismatch repair protein Mlh3 (MutL protein homolog 3)
Target NameNA
Target TypeNA
Gene Age1292 ( ENSG00000119684 )
Evolutionary StageEukaryota
AlphaFoldDBQ9UHC1
Gene CardMLH3
Uniprot IDQ9UHC1
PfamPF01119; PF08676
In ASDno
Allosteric Predictionno (-0.533102604)
Ortholog in AnimalsAlpaca_ MLH3 ( ortholog_one2one )
Dog_ MLH3 ( ortholog_one2one )
GuineaPig_ MLH3 ( ortholog_one2one )
Macaque_ MLH3 ( ortholog_one2one )
Mouse_ Mlh3 ( ortholog_one2one )
Pig_ MLH3 ( ortholog_one2one )
Rat_ Mlh3 ( ortholog_one2one )
Rabbit_ MLH3 ( ortholog_one2one )
OhnologsNA
ParalogsPMS2, MLH1, PMS1
TissueNA
Tissue SpecificityUbiquitous.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs28937870  rs28756978  rs28756979  rs28756981  rs28756982  rs28756983  rs760778201  rs28937871  rs28756984  rs28756985  rs28756986  rs28756987  rs28756988  rs28756989  rs28756990  rs28756991  rs143278116  rs175081  rs175080  rs28756992  rs17102999  rs17782839  rs377337763  rs776639203  rs28756993  rs28757008  rs28757011  rs138006166  rs28939071 
Subcellular location [CC]Nucleus {ECO:0000305}.
Mouse PG classificationNA
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