Gene Information
Gene NameMLC2
OrganismHomo sapiens (Human)
Gene Length172
Protein NamesMyosin regulatory light polypeptide 9 (20 kDa myosin light chain) (LC20) (MLC-2C) (Myosin RLC) (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) (Myosin regulatory light chain MRLC1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP24844
Gene CardMYL9
Uniprot IDP24844
PfamPF13405; PF13833
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificitySmooth muscle tissues and in some, but not all, nonmuscle cells. {ECO:0000269|PubMed:2526655}.
Pharmacological Animal Models0.000730(Chimpanzee);0.342797(Mouse);0.001000(Rat);0.082143(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9CQ19}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q9CQ19}. Note=Colocalizes with F-actin, MYH9 and PIEZO1 at the actomyosin cortex in myoblasts. {ECO:0000250|UniProtKB:Q9CQ19}.
Mouse PG classificationNA
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