| Gene Information | |
|---|---|
| Gene Name | MLC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 377 |
| Protein Names | Membrane protein MLC1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000100427 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q15049 |
| Gene Card | MLC1 |
| Uniprot ID | Q15049 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.416521623) |
| Ortholog in Animals | Alpaca_ MLC1 ( ortholog_one2one ) Dog_ MLC1 ( ortholog_one2one ) GuineaPig_ MLC1 ( ortholog_one2one ) Macaque_ MLC1 ( ortholog_one2one ) Mouse_ Mlc1 ( ortholog_one2one ) Pig_ MLC1 ( ortholog_one2one ) Rat_ Mlc1 ( ortholog_one2one ) Rabbit_ MLC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus. {ECO:0000269|PubMed:11326298}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs80358242 rs281875309 rs281875310 rs281875311 rs121908345 rs80358245 rs281875316 rs281875314 rs121908343 rs121908344 rs6010260 rs281875317 rs281875312 rs281875315 rs121908341 rs80358240 rs281875313 rs11568188 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:22328087}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:22328087}. Endoplasmic reticulum {ECO:0000269|PubMed:22328087}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |