| Gene Information | |
|---|---|
| Gene Name | CDK11B |
| Organism | Homo sapiens (Human) |
| Gene Length | 795 |
| Protein Names | Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1934 ( ENSG00000248333 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P21127 |
| Gene Card | CDK11B |
| Uniprot ID | P21127 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.274719235) |
| Ortholog in Animals | Mouse_ Cdk11b ( ortholog_one2many ) Rat_ Cdk11b ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | CDK14, CDKL2, CDK5, CDKL3, CDK7, CDK3, CDK1, CDKL1, CDK19, CDKL5, CDK6, CDK16, CDK15, CDK4, CDKL4, CDK2, CDK20, CDK9, CDK12, CDK8, CDK10, CDK13, CDK18, CDK17, PRPF4B, CDK11A |
| Tissue | NA |
| Tissue Specificity | Expressed ubiquitously. Some evidence of isoform-specific tissue distribution. {ECO:0000269|PubMed:8195233, ECO:0000269|PubMed:9750192}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs752740049 rs1059831 rs1059830 rs1557687207 rs1241694892 rs200190129 rs1059815 rs1059811 |
| Subcellular location [CC] | Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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