| Gene Information | |
|---|---|
| Gene Name | MKS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 559 |
| Protein Names | Tectonic-like complex member MKS1 (Meckel syndrome type 1 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000011143 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NXB0 |
| Gene Card | MKS1 |
| Uniprot ID | Q9NXB0 |
| Pfam | PF07162 |
| In ASD | no |
| Allosteric Prediction | no (-0.894073621) |
| Ortholog in Animals | Alpaca_ MKS1 ( ortholog_one2one ) Dog_ MKS1 ( ortholog_one2one ) GuineaPig_ MKS1 ( ortholog_one2one ) Macaque_ MKS1 ( ortholog_one2one ) Mouse_ Mks1 ( ortholog_one2one ) Pig_ MKS1 ( ortholog_one2one ) Rat_ Mks1 ( ortholog_one2one ) Rabbit_ MKS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | B9D1, B9D2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs863225205 rs11653070 rs1114167302 rs202112856 rs201845154 rs151023718 rs863225208 rs773684291 rs863225210 rs200865108 rs137853105 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000269|PubMed:26490104}. |
| Mouse PG classification | HPG |
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