| Gene Information | |
|---|---|
| Gene Name | MKP8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 211 |
| Protein Names | Dual specificity protein phosphatase 26 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase SKRP3) (Low-molecular-mass dual-specificity phosphatase 4) (DSP-4) (LDP-4) (Mitogen-activated protein kinase phosphatase 8) (MAP kinase phosphatase 8) (MKP-8) (Novel amplified gene in thyroid anaplastic cancer) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BV47 |
| Gene Card | DUSP26 |
| Uniprot ID | Q9BV47 |
| Pfam | PF00782 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer. {ECO:0000269|PubMed:15796912, ECO:0000269|PubMed:16581800, ECO:0000269|PubMed:16924234, ECO:0000269|PubMed:17001450}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2E0T (X-ray 1.67A ) 4B04 (X-ray 2.20A ) 4HRF (X-ray 1.68A ) 5GTJ (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Nucleus. Golgi apparatus. |
| Mouse PG classification | NA |
| click here to return to the previous page | |