| Gene Information | |
|---|---|
| Gene Name | MKP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 381 |
| Protein Names | Dual specificity protein phosphatase 6 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PYST1) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q16828 |
| Gene Card | DUSP6 |
| Uniprot ID | Q16828 |
| Pfam | PF00782; PF00581 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in keratinocytes (at protein level). {ECO:0000269|PubMed:29043977}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1HZM (NMR - ) 1MKP (X-ray 2.35A ) |
| DBSNP | rs587776978 rs2279574 rs770087 rs139318648 rs143946794 rs12828557 rs146089505 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:8670865}. |
| Mouse PG classification | NA |
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