| Gene Information | |
|---|---|
| Gene Name | TAPBP |
| Organism | Homo sapiens (Human) |
| Gene Length | 448 |
| Protein Names | Tapasin (TPN) (TPSN) (NGS-17) (TAP-associated protein) (TAP-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000112493 ) 3 ( ENSG00000206208 ) 3 ( ENSG00000206281 ) 454 ( ENSG00000231925 ) 3 ( ENSG00000236490 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O15533 |
| Gene Card | TAPBP |
| Uniprot ID | O15533 |
| Pfam | PF07654 |
| In ASD | no |
| Allosteric Prediction | no (-0.765432791) |
| Ortholog in Animals | Alpaca_ TAPBP ( ortholog_one2one ) Dog_ TAPBP ( ortholog_one2one ) GuineaPig_ TAPBP ( ortholog_one2one ) Macaque_ TAPBP ( ortholog_one2one ) Mouse_ Tapbp ( ortholog_one2one ) Pig_ TAPBP ( ortholog_one2one ) Rat_ Tapbp ( ortholog_one2one ) Rabbit_ TAPBP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NCR3LG1, TAPBPL |
| Tissue | NA |
| Tissue Specificity | Neutrophils, mostly in fully differentiated cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3F8U (X-ray 2.60A ) 6ENY (EM 5.80A ) 7QPD (EM 3.73A ) 7TUE (X-ray 3.10A ) 7TUF (X-ray 2.80A ) 7TUG (X-ray 3.90A ) |
| DBSNP | rs2071888 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | LPG |
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