| Gene Information | |
|---|---|
| Gene Name | NPNT |
| Organism | Homo sapiens (Human) |
| Gene Length | 565 |
| Protein Names | Nephronectin (Preosteoblast EGF-like repeat protein with MAM domain) (Protein EGFL6-like) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000168743 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6UXI9 |
| Gene Card | NPNT |
| Uniprot ID | Q6UXI9 |
| Pfam | PF12947; PF07645; PF00629 |
| In ASD | no |
| Allosteric Prediction | no (-0.848886817) |
| Ortholog in Animals | Alpaca_ NPNT ( ortholog_one2one ) Dog_ NPNT ( ortholog_one2one ) GuineaPig_ NPNT ( ortholog_one2one ) Macaque_ NPNT ( ortholog_one2one ) Mouse_ Npnt ( ortholog_one2one ) Pig_ NPNT ( ortholog_one2one ) Rat_ Npnt ( ortholog_one2one ) Rabbit_ NPNT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EGFL6 |
| Tissue | NA |
| Tissue Specificity | Expressed in kidney and lung and to a lower extent in brain, pregnant uterus, placenta, thyroid gland and blood vessels. {ECO:0000269|PubMed:15754038}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35132891 rs4340795 rs35613262 rs35488797 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Trapped on the cell surface or in the extracellular matrix. {ECO:0000250}. |
| Mouse PG classification | NA |
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