| Gene Information | |
|---|---|
| Gene Name | MAPRE3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 281 |
| Protein Names | Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000084764 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UPY8 |
| Gene Card | MAPRE3 |
| Uniprot ID | Q9UPY8 |
| Pfam | PF00307; PF03271 |
| In ASD | no |
| Allosteric Prediction | no (-1.349441177) |
| Ortholog in Animals | Alpaca_ MAPRE3 ( ortholog_one2one ) Dog_ MAPRE3 ( ortholog_one2one ) GuineaPig_ MAPRE3 ( ortholog_one2one ) Macaque_ MAPRE3 ( ortholog_one2one ) Mouse_ Mapre3 ( ortholog_one2one ) Pig_ MAPRE3 ( ortholog_one2one ) Rat_ Mapre3 ( ortholog_one2one ) Rabbit_ MAPRE3 ( ortholog_one2one ) |
| Ohnologs | MAPRE1, MAPRE2 |
| Paralogs | MAPRE2, MAPRE1 |
| Tissue | testis |
| Tissue Specificity | Predominantly expressed in brain and muscle. {ECO:0000269|PubMed:10644998}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.027778(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WYO (NMR - ) 3CO1 (X-ray 1.40A ) 3JAK (EM 3.50A ) 3JAL (EM 3.50A ) 3JAR (EM 3.50A ) 3TQ7 (X-ray 2.30A ) 7SJ9 (EM 3.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10644998, ECO:0000269|PubMed:19255245, ECO:0000269|PubMed:28814570}. Note=Associated with the microtubule network. Detected at the plus end of microtubules. {ECO:0000269|PubMed:10644998, ECO:0000269|PubMed:19255245, ECO:0000269|PubMed:28814570}. |
| Mouse PG classification | NA |
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