| Gene Information | |
|---|---|
| Gene Name | NSRP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 558 |
| Protein Names | Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55) (Nuclear speckle-related protein 70) (NSrp70) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000126653 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H0G5 |
| Gene Card | NSRP1 |
| Uniprot ID | Q9H0G5 |
| Pfam | PF20427; PF09745 |
| In ASD | no |
| Allosteric Prediction | no (-1.846194577) |
| Ortholog in Animals | Alpaca_ NSRP1 ( ortholog_one2one ) Dog_ NSRP1 ( ortholog_one2one ) GuineaPig_ NSRP1 ( ortholog_one2one ) Macaque_ NSRP1 ( ortholog_one2one ) Mouse_ Nsrp1 ( ortholog_one2one ) Pig_ NSRP1 ( ortholog_one2one ) Rat_ Nsrp1 ( ortholog_one2one ) Rabbit_ NSRP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EFCAB5 |
| Tissue | NA |
| Tissue Specificity | Expressed in dendritic cells, T-cells, B-cells and natural killer cells. Expressed in secondary lymphoid organs such as spleen and mesenteric, axillary and brachial lymph nodes. {ECO:0000269|PubMed:21296756}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11544945 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:21296756}. Nucleus speckle {ECO:0000269|PubMed:21296756}. Note=Colocalizes with splicing factors SRSF1 and SRSF2 in speckles. |
| Mouse PG classification | NA |
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