| Gene Information | |
|---|---|
| Gene Name | SHLD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 250 |
| Protein Names | Shieldin complex subunit 3 (REV7-interacting novel NHEJ regulator 1) (Shield complex subunit 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000253251 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6ZNX1 |
| Gene Card | SHLD3 |
| Uniprot ID | Q6ZNX1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.103436554) |
| Ortholog in Animals | Macaque_ SHLD3 ( ortholog_one2one ) Mouse_ Shld3 ( ortholog_one2one ) Pig_ SHLD3 ( ortholog_one2one ) Rat_ Shld3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6K07 (X-ray 2.24A ) 6K08 (X-ray 2.31A ) 6KTO (X-ray 3.45A ) 6M7A (X-ray 1.90A ) 6M7B (X-ray 1.77A ) 6VE5 (X-ray 2.00A ) 6WW9 (X-ray 2.70A ) 6WWA (X-ray 3.80A ) 7L9P (EM 3.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Chromosome {ECO:0000269|PubMed:29656893}. Note=Recruited to sites of chromosomal double-stranded breaks during G1 and S phase of the cell cycle. {ECO:0000269|PubMed:29656893}. |
| Mouse PG classification | NA |
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