Gene Information
Gene NameSH3BP2
OrganismHomo sapiens (Human)
Gene Length561
Protein NamesSH3 domain-binding protein 2 (3BP-2)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000087266 )
Evolutionary StageEumetazoa
AlphaFoldDBP78314
Gene CardSH3BP2
Uniprot IDP78314
PfamPF00169; PF00017
In ASDno
Allosteric Predictionyes (0.059449202)
Ortholog in AnimalsAlpaca_ SH3BP2 ( ortholog_one2one )
Dog_ SH3BP2 ( ortholog_one2one )
GuineaPig_ SH3BP2 ( ortholog_one2one )
Macaque_ SH3BP2 ( ortholog_one2one )
Mouse_ Sh3bp2 ( ortholog_one2one )
Pig_ SH3BP2 ( ortholog_one2one )
Rat_ Sh3bp2 ( ortholog_one2one )
Rabbit_ SH3BP2 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9734812}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2CR4  (NMR  3TWR  (X-ray  1.55A 
DBSNP rs121909149  rs121909149  rs121909146  rs121909146  rs121909146  rs28938171  rs28938170 
Subcellular location [CC]NA
Mouse PG classificationNA
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