| Gene Information | |
|---|---|
| Gene Name | RAMP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 148 |
| Protein Names | Receptor activity-modifying protein 1 (Calcitonin-receptor-like receptor activity-modifying protein 1) (CRLR activity-modifying protein 1) |
| Target Name | receptor activity-modifying protein 1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000132329 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O60894 |
| Gene Card | RAMP1 |
| Uniprot ID | O60894 |
| Pfam | PF04901 |
| In ASD | no |
| Allosteric Prediction | yes (0.298649178) |
| Ortholog in Animals | Alpaca_ RAMP1 ( ortholog_one2one ) Dog_ RAMP1 ( ortholog_one2one ) GuineaPig_ RAMP1 ( ortholog_one2one ) Macaque_ RAMP1 ( ortholog_one2one ) Mouse_ Ramp1 ( ortholog_one2one ) Pig_ RAMP1 ( ortholog_one2one ) Rat_ Ramp1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RAMP3, RAMP2 |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract. {ECO:0000269|PubMed:9620797}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2YX8 (X-ray 2.40A ) 3N7P (X-ray 2.80A ) 3N7R (X-ray 2.90A ) 3N7S (X-ray 2.10A ) 4RWG (X-ray 2.44A ) 5V6Y (X-ray 2.80A ) 6D1U (X-ray 2.05A ) 6E3Y (EM 3.30A ) 6UMG (X-ray 2.70A ) 6ZHO (X-ray 1.60A ) 6ZIS (X-ray 1.73A ) 7KNT (EM 3.15A ) 7KNU (EM 3.49A ) 7P0F (X-ray 1.85A ) 7P0I (X-ray 2.30A ) 7TYF (EM 2.20A ) 7TYW (EM 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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