| Gene Information | |
|---|---|
| Gene Name | CCAR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1150 |
| Protein Names | Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000060339 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8IX12 |
| Gene Card | CCAR1 |
| Uniprot ID | Q8IX12 |
| Pfam | PF19257; PF14443; PF19256; PF14444; PF02037 |
| In ASD | no |
| Allosteric Prediction | no (-0.999847204) |
| Ortholog in Animals | Alpaca_ CCAR1 ( ortholog_one2one ) Dog_ CCAR1 ( ortholog_one2one ) GuineaPig_ CCAR1 ( ortholog_one2one ) Macaque_ CCAR1 ( ortholog_one2one ) Mouse_ Ccar1 ( ortholog_one2one ) Pig_ CCAR1 ( ortholog_one2one ) Rat_ Ccar1 ( ortholog_one2one ) Rabbit_ CCAR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CCAR2 |
| Tissue | NA |
| Tissue Specificity | Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors. {ECO:0000269|PubMed:12816952}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1782338 rs1060145 rs11542602 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000269|PubMed:12816952}. |
| Mouse PG classification | NA |
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