| Gene Information | |
|---|---|
| Gene Name | GRIN2D |
| Organism | Homo sapiens (Human) |
| Gene Length | 1336 |
| Protein Names | Glutamate receptor ionotropic, NMDA 2D (GluN2D) (EB11) (Glutamate [NMDA] receptor subunit epsilon-4) (N-methyl D-aspartate receptor subtype 2D) (NMDAR2D) (NR2D) |
| Target Name | glutamate receptor ionotropic, nmda 2d |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000105464 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O15399 |
| Gene Card | GRIN2D |
| Uniprot ID | O15399 |
| Pfam | PF01094; PF00060; PF10613 |
| In ASD | yes |
| Allosteric Prediction | yes (0.999803009) |
| Ortholog in Animals | Dog_ GRIN2D ( ortholog_one2one ) GuineaPig_ GRIN2D ( ortholog_one2one ) Macaque_ GRIN2D ( ortholog_one2one ) Mouse_ Grin2d ( ortholog_one2one ) Pig_ GRIN2D ( ortholog_one2one ) Rat_ Grin2d ( ortholog_one2one ) Rabbit_ GRIN2D ( ortholog_one2one ) |
| Ohnologs | GRIN2C, GRIN2A, GRIN3A |
| Paralogs | GRIN3A, GRIN2A, GRIK5, GRIN2C, GRID1, GRID2, GRIK3, GRIN1, GRIK4, GRIA3, GRIK1, GRIA2, GRIA1, GRIN3B, GRIK2, GRIA4, GRIN2B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1259830926 rs886040861 rs750543659 rs781567305 rs571334598 rs1225338399 rs191119443 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:26875626, ECO:0000269|PubMed:28126851, ECO:0000269|PubMed:9489750}; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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