Gene Information
Gene NameANKS6
OrganismHomo sapiens (Human)
Gene Length871
Protein NamesAnkyrin repeat and SAM domain-containing protein 6 (Ankyrin repeat domain-containing protein 14) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000165138 )
Evolutionary StageEumetazoa
AlphaFoldDBQ68DC2
Gene CardANKS6
Uniprot IDQ68DC2
PfamPF12796; PF00536
In ASDno
Allosteric Predictionno (-1.117847935)
Ortholog in AnimalsAlpaca_ ANKS6 ( ortholog_one2one )
Dog_ ANKS6 ( ortholog_one2one )
GuineaPig_ ANKS6 ( ortholog_one2one )
Macaque_ ANKS6 ( ortholog_one2one )
Mouse_ Anks6 ( ortholog_one2one )
Pig_ ANKS6 ( ortholog_one2one )
Rat_ Anks6 ( ortholog_one2one )
Rabbit_ ANKS6 ( ortholog_one2one )
OhnologsNA
ParalogsBICC1, HDLBP
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.010990(Rat);0.200000(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4NL9  (X-ray  1.50A 
DBSNP rs41283630  rs763855876  rs377750405  rs749102463  rs6415847  rs79414550 
Subcellular location [CC]Cell projection, cilium {ECO:0000250|UniProtKB:Q6GQX6}. Cytoplasm {ECO:0000250|UniProtKB:P0C0T2}. Note=Localizes to the proximal region of the primary cilium in the presence of INVS. {ECO:0000250|UniProtKB:Q6GQX6}.
Mouse PG classificationHPG
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