| Gene Information | |
|---|---|
| Gene Name | LONP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 852 |
| Protein Names | Lon protease homolog 2, peroxisomal (EC 3.4.21.53) (Lon protease-like protein 2) (Lon protease 2) (Peroxisomal Lon protease) (pLon) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000102910 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q86WA8 |
| Gene Card | LONP2 |
| Uniprot ID | Q86WA8 |
| Pfam | PF00004; PF05362; PF02190 |
| In ASD | no |
| Allosteric Prediction | no (-0.389655145) |
| Ortholog in Animals | Alpaca_ LONP2 ( ortholog_one2one ) Dog_ LONP2 ( ortholog_one2one ) GuineaPig_ LONP2 ( ortholog_one2one ) Macaque_ LONP2 ( ortholog_one2one ) Mouse_ Lonp2 ( ortholog_one2one ) Pig_ LONP2 ( ortholog_one2one ) Rat_ Lonp2 ( ortholog_one2one ) Rabbit_ LONP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LONP1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with high levels in the liver, kidney and pancreas. {ECO:0000269|PubMed:18281296}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Peroxisome matrix {ECO:0000255|HAMAP-Rule:MF_03121, ECO:0000269|PubMed:14561759, ECO:0000269|PubMed:18281296, ECO:0000269|PubMed:22002062}. |
| Mouse PG classification | NA |
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