| Gene Information | |
|---|---|
| Gene Name | BLVRB |
| Organism | Homo sapiens (Human) |
| Gene Length | 206 |
| Protein Names | Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR) |
| Target Name | flavin reductase (nadph) |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000090013 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P30043 |
| Gene Card | BLVRB |
| Uniprot ID | P30043 |
| Pfam | PF13460 |
| In ASD | no |
| Allosteric Prediction | no (-0.277711176) |
| Ortholog in Animals | Alpaca_ BLVRB ( ortholog_one2one ) Dog_ BLVRB ( ortholog_one2one ) GuineaPig_ BLVRB ( ortholog_one2one ) Macaque_ BLVRB ( ortholog_one2one ) Mouse_ Blvrb ( ortholog_one2one ) Pig_ BLVRB ( ortholog_one2one ) Rabbit_ BLVRB ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in liver and erythrocytes. At lower levels in heart, lung, adrenal gland and cerebrum. {ECO:0000269|PubMed:7929092}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1HDO (X-ray 1.15A ) 1HE2 (X-ray 1.20A ) 1HE3 (X-ray 1.40A ) 1HE4 (X-ray 1.40A ) 1HE5 (X-ray 1.50A ) 5OOG (X-ray 1.33A ) 5OOH (X-ray 1.20A ) 6OPL (X-ray 1.37A ) 7ER6 (X-ray 1.60A ) 7ER7 (X-ray 1.70A ) 7ER8 (X-ray 1.45A ) 7ER9 (X-ray 1.45A ) 7ERA (X-ray 1.35A ) 7ERB (X-ray 1.50A ) 7ERC (X-ray 1.50A ) 7ERD (X-ray 2.00A ) 7ERE (X-ray 1.60A ) |
| DBSNP | rs11547746 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:7929092}. |
| Mouse PG classification | NA |
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