| Gene Information | |
|---|---|
| Gene Name | CHMP1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 199 |
| Protein Names | Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000255112 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7LBR1 |
| Gene Card | CHMP1B |
| Uniprot ID | Q7LBR1 |
| Pfam | PF03357 |
| In ASD | no |
| Allosteric Prediction | no (-1.272272195) |
| Ortholog in Animals | Mouse_ Chmp1b ( ortholog_one2one ) Rat_ RGD1566265 ( ortholog_one2one ) Rabbit_ CHMP1B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CHMP1A, CHMP2B, CHMP3, CHMP2A |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta and brain. {ECO:0000269|PubMed:11474171}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.640725(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3EAB (X-ray 2.50A ) 3JC1 (EM 4.00A ) 4TXQ (X-ray 2.21A ) 4TXR (X-ray 1.00A ) 6E8G (EM 2.90A ) 6TZ4 (EM 3.20A ) 6TZ5 (EM 3.10A ) 6TZ9 (EM 6.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol. Endosome. Late endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Localizes to the midbody of dividing cells, colocalizing with CEP55 and CHMP5. Localized at the periphery of the Fleming body. |
| Mouse PG classification | NA |
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