| Gene Information | |
|---|---|
| Gene Name | CACUL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 369 |
| Protein Names | CDK2-associated and cullin domain-containing protein 1 (Cdk-associated cullin 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000151893 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q86Y37 |
| Gene Card | CACUL1 |
| Uniprot ID | Q86Y37 |
| Pfam | PF00888 |
| In ASD | no |
| Allosteric Prediction | no (-1.072281857) |
| Ortholog in Animals | Alpaca_ CACUL1 ( ortholog_one2one ) Dog_ CACUL1 ( ortholog_one2one ) GuineaPig_ CACUL1 ( ortholog_one2one ) Macaque_ CACUL1 ( ortholog_one2one ) Mouse_ Cacul1 ( ortholog_one2one ) Pig_ CACUL1 ( ortholog_one2one ) Rat_ Cacul1 ( ortholog_one2one ) Rabbit_ CACUL1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CUL4A, CUL3, CUL2, ANAPC2, CUL1, CUL5, CUL4B |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed with highest expression in the mammary gland and large intestine. Highly expressed in cancer tissues and cancer cell lines. During cell cycle progression expression is high in G1/S, low in the middle of S phase, and increases again in S/G2 phase. {ECO:0000269|PubMed:19829063}. |
| Pharmacological Animal Models | 0.012047(Chimpanzee);0.011588(Mouse);NULL(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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