| Gene Information | |
|---|---|
| Gene Name | DZIP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1208 |
| Protein Names | E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000198919 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86Y13 |
| Gene Card | DZIP3 |
| Uniprot ID | Q86Y13 |
| Pfam | PF18738; PF19179; PF13639 |
| In ASD | no |
| Allosteric Prediction | no (-0.576481521) |
| Ortholog in Animals | Alpaca_ DZIP3 ( ortholog_one2one ) Dog_ DZIP3 ( ortholog_one2one ) GuineaPig_ DZIP3 ( ortholog_one2one ) Macaque_ DZIP3 ( ortholog_one2one ) Mouse_ Dzip3 ( ortholog_one2one ) Pig_ DZIP3 ( ortholog_one2one ) Rat_ Dzip3 ( ortholog_one2one ) Rabbit_ DZIP3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RNF139, AMFR, SYVN1, RNF145 |
| Tissue | NA |
| Tissue Specificity | Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas. {ECO:0000269|PubMed:12538761}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12538761}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |