Gene Information
Gene NameAGGF1
OrganismHomo sapiens (Human)
Gene Length714
Protein NamesAngiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (hVG5Q) (G patch domain-containing protein 7) (Vasculogenesis gene on 5q protein)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000164252 )
Evolutionary StageEumetazoa
AlphaFoldDBQ8N302
Gene CardAGGF1
Uniprot IDQ8N302
PfamPF00498; PF01585; PF17780
In ASDno
Allosteric Predictionno (-0.709770707)
Ortholog in AnimalsAlpaca_ AGGF1 ( ortholog_one2one )
Dog_ AGGF1 ( ortholog_one2one )
GuineaPig_ AGGF1 ( ortholog_one2one )
Mouse_ Aggf1 ( ortholog_one2one )
Pig_ AGGF1 ( ortholog_one2one )
Rat_ Aggf1 ( ortholog_one2one )
Rabbit_ AGGF1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed. Expressed in endothelial cells, vascular smooth muscle cells and osteoblasts. Expressed in umbilical vein endothelial cells and microvascular endothelial cells. {ECO:0000269|PubMed:14961121}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34203073  rs9715897  rs17856835  rs34400049 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:14961121}. Secreted {ECO:0000269|PubMed:14961121}. Note=Cytoplasmic in microvascular endothelial cells. Upon angiogenesis, when endothelial cell tube formation is initiated, it is secreted.
Mouse PG classificationNA
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