| Gene Information | |
|---|---|
| Gene Name | SNAI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 264 |
| Protein Names | Zinc finger protein SNAI1 (Protein snail homolog 1) (Protein sna) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000124216 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95863 |
| Gene Card | SNAI1 |
| Uniprot ID | O95863 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | yes (0.010426701) |
| Ortholog in Animals | Alpaca_ SNAI1 ( ortholog_one2one ) Dog_ SNAI1 ( ortholog_one2one ) GuineaPig_ SNAI1 ( ortholog_one2one ) Macaque_ SNAI1 ( ortholog_one2one ) Mouse_ Snai1 ( ortholog_one2one ) Pig_ SNAI1 ( ortholog_one2one ) Rat_ Snai1 ( ortholog_one2one ) Rabbit_ SNAI1 ( ortholog_one2one ) |
| Ohnologs | SNAI2, SNAI3 |
| Paralogs | ZNF575, ZNF276, HIC1, ZNF653, ZNF362, ZNF410, PATZ1, MTF1, PRDM1, HIC2, ZNF76, ZFP91, PRDM6, ZNF296, ZBTB1, SNAI3, SNAI2, ZBTB20, ZNF281, MAZ, ZBTB18, ZNF143, ZBTB16, ZNF148, ZBTB32, ZBTB45, ZBTB7C, ZBTB42, ZNF451, ZNF692, PRDM14, VEZF1, SCRT2, SCRT1, ZNF384, PRDM10 |
| Tissue | adipose.tissue |
| Tissue Specificity | Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines. {ECO:0000269|PubMed:10655587}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.305910(Mouse);0.078890(Rat);0.027778(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2Y48 (X-ray 3.00A ) 3W5K (X-ray 2.60A ) 3ZMT (X-ray 3.10A ) 4QLI (X-ray 1.45A ) |
| DBSNP | rs34261470 rs4647958 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15448698, ECO:0000269|PubMed:15833848, ECO:0000269|PubMed:20389281, ECO:0000269|PubMed:24699649, ECO:0000269|PubMed:25893292}. Cytoplasm {ECO:0000269|PubMed:15448698, ECO:0000269|PubMed:15833848}. Note=Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. {ECO:0000269|PubMed:15448698}. |
| Mouse PG classification | NA |
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