| Gene Information | |
|---|---|
| Gene Name | MAML1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1016 |
| Protein Names | Mastermind-like protein 1 (Mam-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000161021 ) 3 ( ENSG00000283780 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q92585 |
| Gene Card | MAML1 |
| Uniprot ID | Q92585 |
| Pfam | PF09596 |
| In ASD | no |
| Allosteric Prediction | no (-0.58473421) |
| Ortholog in Animals | Alpaca_ MAML1 ( ortholog_one2one ) Dog_ MAML1 ( ortholog_one2one ) GuineaPig_ MAML1 ( ortholog_one2one ) Macaque_ MAML1 ( ortholog_one2one ) Mouse_ Maml1 ( ortholog_one2one ) Pig_ MAML1 ( ortholog_one2one ) Rat_ Maml1 ( ortholog_one2one ) Rabbit_ MAML1 ( ortholog_one2one ) |
| Ohnologs | MAML3 |
| Paralogs | MAML3, MAML2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in heart, pancreas, peripheral blood leukocytes and spleen. {ECO:0000269|PubMed:11101851}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002419(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2F8X (X-ray 3.25A ) 3NBN (X-ray 3.45A ) 3V79 (X-ray 3.85A ) 6SMV (X-ray 2.14A ) |
| DBSNP | rs41285557 rs6895902 |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:11101851}. Note=Nuclear, in a punctate manner. |
| Mouse PG classification | NA |
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