| Gene Information | |
|---|---|
| Gene Name | DENND5B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1274 |
| Protein Names | DENN domain-containing protein 5B (Rab6IP1-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000170456 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q6ZUT9 |
| Gene Card | DENND5B |
| Uniprot ID | Q6ZUT9 |
| Pfam | PF03455; PF02141; PF01477; PF02759; PF03456 |
| In ASD | no |
| Allosteric Prediction | no (-0.958004539) |
| Ortholog in Animals | Alpaca_ DENND5B ( ortholog_one2one ) Dog_ DENND5B ( ortholog_one2one ) GuineaPig_ DENND5B ( ortholog_one2one ) Macaque_ DENND5B ( ortholog_one2one ) Mouse_ Dennd5b ( ortholog_one2one ) Pig_ DENND5B ( ortholog_one2one ) Rat_ Dennd5b ( ortholog_one2one ) Rabbit_ DENND5B ( ortholog_one2one ) |
| Ohnologs | DENND5A |
| Paralogs | PKDREJ, PKD1L2, PKD2L2, PKD2L1, LOXHD1, PKD1L3, PKD1L1, PKD1, PKD2, DENND5A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4930979 rs1056320 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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