| Gene Information | |
|---|---|
| Gene Name | SLC48A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 146 |
| Protein Names | Heme transporter HRG1 (Heme-responsive gene 1 protein homolog) (HRG-1) (hHRG-1) (Solute carrier family 48 member 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000211584 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6P1K1 |
| Gene Card | SLC48A1 |
| Uniprot ID | Q6P1K1 |
| Pfam | PF16954 |
| In ASD | no |
| Allosteric Prediction | no (-0.950232672) |
| Ortholog in Animals | Alpaca_ SLC48A1 ( ortholog_one2one ) Dog_ SLC48A1 ( ortholog_one2one ) GuineaPig_ SLC48A1 ( ortholog_one2one ) Macaque_ SLC48A1 ( ortholog_one2one ) Mouse_ Slc48a1 ( ortholog_one2one ) Pig_ SLC48A1 ( ortholog_one2one ) Rat_ Slc48a1 ( ortholog_one2one ) Rabbit_ SLC48A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the brain, kidney, heart and skeletal muscle. Moderately expressed in the liver, lung, placenta and small intestine. {ECO:0000269|PubMed:18418376}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endosome membrane {ECO:0000269|PubMed:18418376}; Multi-pass membrane protein {ECO:0000269|PubMed:18418376}. Lysosome membrane {ECO:0000269|PubMed:18418376}; Multi-pass membrane protein {ECO:0000269|PubMed:18418376}. |
| Mouse PG classification | NA |
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