| Gene Information | |
|---|---|
| Gene Name | PPP1R14C |
| Organism | Homo sapiens (Human) |
| Gene Length | 165 |
| Protein Names | Protein phosphatase 1 regulatory subunit 14C (Kinase-enhanced PP1 inhibitor) (PKC-potentiated PP1 inhibitory protein) (Serologically defined breast cancer antigen NY-BR-81) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000198729 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8TAE6 |
| Gene Card | PPP1R14C |
| Uniprot ID | Q8TAE6 |
| Pfam | PF05361 |
| In ASD | no |
| Allosteric Prediction | no (-1.135840717) |
| Ortholog in Animals | Alpaca_ PPP1R14C ( ortholog_one2one ) Dog_ PPP1R14C ( ortholog_one2one ) Macaque_ PPP1R14C ( ortholog_one2one ) Mouse_ Ppp1r14c ( ortholog_one2one ) Pig_ PPP1R14C ( ortholog_one2one ) Rat_ Ppp1r14c ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPP1R14B, PPP1R14D, PPP1R14A |
| Tissue | NA |
| Tissue Specificity | Detected in breast cancer. {ECO:0000269|PubMed:12747765}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2297672 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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