| Gene Information | |
|---|---|
| Gene Name | GIG31 |
| Organism | Homo sapiens (Human) |
| Gene Length | 211 |
| Protein Names | Regulator of G-protein signaling 2 (RGS2) (Cell growth-inhibiting gene 31 protein) (G0/G1 switch regulatory protein 8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P41220 |
| Gene Card | RGS2 |
| Uniprot ID | P41220 |
| Pfam | PF00615 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL). {ECO:0000269|PubMed:7643615}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2AF0 (X-ray 2.30A ) 2V4Z (X-ray 2.80A ) 4EKC (X-ray 7.40A ) 4EKD (X-ray 2.71A ) |
| DBSNP | rs141030117 rs141030117 rs145125159 rs142499684 rs193051407 rs74466425 rs148489044 rs201233692 rs200339834 rs80221024 rs140811638 rs139237239 rs146862218 rs369752935 rs112707798 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000269|PubMed:11278586, ECO:0000269|PubMed:17901199, ECO:0000269|PubMed:28784619}. Cytoplasm {ECO:0000269|PubMed:11278586, ECO:0000269|PubMed:17901199}. Nucleus, nucleolus {ECO:0000269|PubMed:11278586, ECO:0000269|PubMed:17901199}.; [Isoform 2]: Cell membrane {ECO:0000269|PubMed:17901199}. Cytoplasm {ECO:0000269|PubMed:17901199}. Nucleus, nucleolus {ECO:0000269|PubMed:17901199}.; [Isoform 3]: Cell membrane {ECO:0000269|PubMed:17901199}. Cytoplasm {ECO:0000269|PubMed:17901199}. Nucleus, nucleolus {ECO:0000269|PubMed:17901199}.; [Isoform 4]: Cell membrane {ECO:0000269|PubMed:17901199}. Mitochondrion {ECO:0000269|PubMed:17901199}. |
| Mouse PG classification | NA |
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