Gene Information
Gene NameSLC28A1
OrganismHomo sapiens (Human)
Gene Length649
Protein NamesSodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (hCNT1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000156222 )
Evolutionary StageEuk+Bac
AlphaFoldDBO00337
Gene CardSLC28A1
Uniprot IDO00337
PfamPF07670; PF07662; PF01773
In ASDno
Allosteric Predictionyes (0.214393969)
Ortholog in AnimalsAlpaca_ SLC28A1 ( ortholog_one2one )
GuineaPig_ SLC28A1 ( ortholog_one2one )
Macaque_ SLC28A1 ( ortholog_one2one )
Mouse_ Slc28a1 ( ortholog_one2one )
Pig_ SLC28A1 ( ortholog_one2one )
Rat_ Slc28a1 ( ortholog_one2one )
Rabbit_ SLC28A1 ( ortholog_one2one )
OhnologsSLC28A3
ParalogsSLC28A2, SLC28A3
Tissueduodenum, kidney, liver, small.intestine
Tissue SpecificityExpressed in kidney. {ECO:0000269|PubMed:9124315}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2290272  rs45523532  rs8187758  rs1174011667  rs2242047  rs2242046  rs45584739 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:21998139};
Multi-pass membrane protein {ECO:0000255}.
Mouse PG classificationNA
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