| Gene Information | |
|---|---|
| Gene Name | MOV10L1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1211 |
| Protein Names | RNA helicase Mov10l1 (EC 3.6.4.13) (Moloney leukemia virus 10-like protein 1) (MOV10-like protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000073146 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BXT6 |
| Gene Card | MOV10L1 |
| Uniprot ID | Q9BXT6 |
| Pfam | PF13086; PF13087 |
| In ASD | no |
| Allosteric Prediction | no (-0.660167427) |
| Ortholog in Animals | Alpaca_ MOV10L1 ( ortholog_one2one ) Dog_ MOV10L1 ( ortholog_one2one ) GuineaPig_ MOV10L1 ( ortholog_one2one ) Macaque_ MOV10L1 ( ortholog_one2one ) Mouse_ Mov10l1 ( ortholog_one2one ) Rat_ Mov10l1 ( ortholog_one2one ) Rabbit_ MOV10L1 ( ortholog_one2one ) |
| Ohnologs | MOV10 |
| Paralogs | SETX, AQR, UPF1, DNA2, IGHMBP2, HELZ, ZNFX1, MOV10, HELZ2, CT55 |
| Tissue | testis |
| Tissue Specificity | [Isoform 1]: Specifically expressed in testis. {ECO:0000269|PubMed:11279525}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12628964 rs9617066 rs3810971 rs760749 rs2340601 rs3736689 rs2272837 rs2272843 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q99MV5}. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. {ECO:0000250|UniProtKB:Q99MV5}. |
| Mouse PG classification | NA |
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