Gene Information
Gene NameVSIG10L
OrganismHomo sapiens (Human)
Gene Length867
Protein NamesV-set and immunoglobulin domain-containing protein 10-like (VSIG10-like protein)
Target NameNA
Target TypeNA
Gene Age382 ( ENSG00000186806 )
Evolutionary StageEumetazoa
AlphaFoldDBQ86VR7
Gene CardVSIG10L
Uniprot IDQ86VR7
PfamPF13895
In ASDno
Allosteric Predictionno (-1.727241927)
Ortholog in AnimalsAlpaca_ VSIG10L ( ortholog_one2one )
Dog_ VSIG10L ( ortholog_one2one )
GuineaPig_ VSIG10L ( ortholog_one2one )
Macaque_ VSIG10L ( ortholog_one2one )
Mouse_ Vsig10l ( ortholog_one2one )
Pig_ VSIG10L ( ortholog_one2one )
Rat_ Vsig10l ( ortholog_one2one )
OhnologsNA
ParalogsCNTN5, CNTN2, NFASC, ROBO2, SDK1, SDK2, CNTN3, HMCN2, CNTN6, DSCAML1, CNTN1, IGDCC4, IGSF21, VCAM1, ROBO1, L1CAM, BOC, DCC, IGDCC3, ROBO4, IGSF9, VSIG10, DSCAM, CDON, NCAM1, ROBO3, CHL1, NRCAM, NEO1, IGSF9B, MXRA5, IGSF10, PTPRQ, NCAM2, PRTG, CNTN4
Tissueesophagus, salivary.gland, parotid.gland, submandibular.gland, tongue, esophagus.mucosa
Tissue SpecificityExpressed in the esophagus, particularly in the suprabasilar layers of the epithelium. Expression is largely reduced in esophageal metaplasia, dysplasia, and adenocarcinoma lesions. {ECO:0000269|PubMed:27467440}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs10414211  rs7259266  rs34380065  rs57710066  rs1263178238  rs377207472 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass type I membrane protein {ECO:0000305}.
Mouse PG classificationNA
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