| Gene Information | |
|---|---|
| Gene Name | HLA-DMA |
| Organism | Homo sapiens (Human) |
| Gene Length | 261 |
| Protein Names | HLA class II histocompatibility antigen, DM alpha chain (MHC class II antigen DMA) (Really interesting new gene 6 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000204257 ) 3 ( ENSG00000239463 ) 3 ( ENSG00000241394 ) 3 ( ENSG00000242361 ) 3 ( ENSG00000242685 ) 3 ( ENSG00000243189 ) 3 ( ENSG00000243215 ) 3 ( ENSG00000243719 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | P28067 |
| Gene Card | HLA-DMA |
| Uniprot ID | P28067 |
| Pfam | PF07654; PF00993 |
| In ASD | no |
| Allosteric Prediction | no (-0.234061493) |
| Ortholog in Animals | Dog_ DLA-DMA ( ortholog_one2one ) GuineaPig_ HLA-DMA ( ortholog_one2one ) Mouse_ H2-DMa ( ortholog_one2one ) Pig_ SLA-DMA ( ortholog_one2one ) Rat_ RT1-DMa ( ortholog_one2one ) Rabbit_ HLA-DMA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HLA-DPB1, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DQA1, HLA-DQA2, HLA-DOB, HLA-DRA, HLA-DRB5, HLA-DRB1, B2M, HLA-DQB1, HLA-DQB2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.044444(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1HDM (X-ray 2.50A ) 2BC4 (X-ray 2.27A ) 4FQX (X-ray 2.60A ) 4GBX (X-ray 3.00A ) |
| DBSNP | rs1063478 rs6926628 rs17214044 rs41555121 rs9469319 |
| Subcellular location [CC] | Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Localizes to late endocytic compartment. Associates with lysosome membranes. |
| Mouse PG classification | NA |
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