| Gene Information | |
|---|---|
| Gene Name | DDRGK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 314 |
| Protein Names | DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 78 ( ENSG00000198171 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96HY6 |
| Gene Card | DDRGK1 |
| Uniprot ID | Q96HY6 |
| Pfam | PF09756 |
| In ASD | no |
| Allosteric Prediction | no (-1.148560991) |
| Ortholog in Animals | Alpaca_ DDRGK1 ( ortholog_one2one ) Dog_ DDRGK1 ( ortholog_one2one ) GuineaPig_ DDRGK1 ( ortholog_one2one ) Macaque_ DDRGK1 ( ortholog_one2one ) Mouse_ Ddrgk1 ( ortholog_one2one ) Pig_ DDRGK1 ( ortholog_one2one ) Rat_ Ddrgk1 ( ortholog_one2one ) Rabbit_ DDRGK1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed (at protein level). In the brain, highest levels in medulla oblongata, followed by cerebral cortex, cerebellum and frontal lobe. {ECO:0000269|PubMed:20018847, ECO:0000269|PubMed:20036718}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.002657(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11591 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000269|PubMed:20018847, ECO:0000269|PubMed:32160526}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:32160526}. Note=Localizes to the endoplasmic reticulum membrane in response to endoplasmic reticulum stress. {ECO:0000269|PubMed:32160526}. |
| Mouse PG classification | NA |
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