Gene Information
Gene NameMIS18BP1
OrganismHomo sapiens (Human)
Gene Length1132
Protein NamesMis18-binding protein 1 (Kinetochore-associated protein KNL-2 homolog) (HsKNL-2) (P243)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000129534 )
Evolutionary StageEukaryota
AlphaFoldDBQ6P0N0
Gene CardMIS18BP1
Uniprot IDQ6P0N0
PfamPF00249; PF09133
In ASDno
Allosteric Predictionno (-0.449232777)
Ortholog in AnimalsAlpaca_ MIS18BP1 ( ortholog_one2one )
Dog_ MIS18BP1 ( ortholog_one2one )
GuineaPig_ MIS18BP1 ( ortholog_one2one )
Macaque_ MIS18BP1 ( ortholog_one2one )
Mouse_ Mis18bp1 ( ortholog_one2one )
Pig_ MIS18BP1 ( ortholog_one2one )
Rat_ Mis18bp1 ( ortholog_one2one )
Rabbit_ MIS18BP1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1WGX  (NMR 
DBSNP rs1269008  rs34168608  rs34101857  rs34402741 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:17199038}. Chromosome, centromere {ECO:0000269|PubMed:17199038}. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin. {ECO:0000269|PubMed:17199038}.
Mouse PG classificationNA
click here to return to the previous page