| Gene Information | |
|---|---|
| Gene Name | TMPO |
| Organism | Homo sapiens (Human) |
| Gene Length | 454 |
| Protein Names | Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Cleaved into: Thymopoietin (TP) (Splenin); Thymopentin (TP5)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000120802 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P42167 |
| Gene Card | TMPO |
| Uniprot ID | P42167 |
| Pfam | PF03020; PF08198 |
| In ASD | no |
| Allosteric Prediction | no (-0.608263068) |
| Ortholog in Animals | Dog_ TMPO ( ortholog_one2one ) GuineaPig_ TMPO ( ortholog_one2one ) Macaque_ TMPO ( ortholog_one2one ) Mouse_ Tmpo ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LEMD1 |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues. Most abundant in adult thymus and fetal liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7133258 rs1058288 |
| Subcellular location [CC] | Nucleus inner membrane; Single-pass type II membrane protein. Note=Tightly associated with the nuclear lamina.; [Isoform Zeta]: Cytoplasm {ECO:0000269|PubMed:18403046}. |
| Mouse PG classification | NA |
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