| Gene Information | |
|---|---|
| Gene Name | SIN3A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1273 |
| Protein Names | Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000169375 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96ST3 |
| Gene Card | SIN3A |
| Uniprot ID | Q96ST3 |
| Pfam | PF02671; PF08295; PF16879 |
| In ASD | no |
| Allosteric Prediction | no (-0.219311676) |
| Ortholog in Animals | Alpaca_ SIN3A ( ortholog_one2one ) Dog_ SIN3A ( ortholog_one2one ) GuineaPig_ SIN3A ( ortholog_one2one ) Macaque_ SIN3A ( ortholog_one2one ) Mouse_ Sin3a ( ortholog_one2one ) Pig_ SIN3A ( ortholog_one2one ) Rat_ Sin3a ( ortholog_one2one ) Rabbit_ SIN3A ( ortholog_one2one ) |
| Ohnologs | SIN3B |
| Paralogs | SIN3B |
| Tissue | NA |
| Tissue Specificity | Expressed in the developing brain, with highest levels of expression detected in the ventricular zone of various cortical regions. {ECO:0000269|PubMed:27399968}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001890(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs60213317 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00810, ECO:0000269|PubMed:16820529}. Nucleus, nucleolus {ECO:0000269|PubMed:16820529}. Note=Recruited to the nucleolus by SAP30L. |
| Mouse PG classification | NA |
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