| Gene Information | |
|---|---|
| Gene Name | BRI3BP |
| Organism | Homo sapiens (Human) |
| Gene Length | 251 |
| Protein Names | BRI3-binding protein (I3-binding protein) (Cervical cancer 1 proto-oncogene-binding protein KG19) (HCCRBP-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000184992 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8WY22 |
| Gene Card | BRI3BP |
| Uniprot ID | Q8WY22 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.399656234) |
| Ortholog in Animals | Alpaca_ BRI3BP ( ortholog_one2one ) Dog_ BRI3BP ( ortholog_one2one ) GuineaPig_ BRI3BP ( ortholog_one2one ) Macaque_ BRI3BP ( ortholog_one2one ) Mouse_ Bri3bp ( ortholog_one2one ) Pig_ BRI3BP ( ortholog_one2one ) Rat_ Bri3bp ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Most abundantly expressed in brain, liver and kidney (PubMed:11860200). Overexpressed in leukemia and lymphoma cell lines, as well as in various carcinomas (PubMed:17943721). {ECO:0000269|PubMed:11860200, ECO:0000269|PubMed:17943721}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000305|PubMed:17943721}; Multi-pass membrane protein {ECO:0000305|PubMed:17943721}. |
| Mouse PG classification | NA |
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