| Gene Information | |
|---|---|
| Gene Name | NCKIPSD |
| Organism | Homo sapiens (Human) |
| Gene Length | 722 |
| Protein Names | NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (54 kDa vimentin-interacting protein) (VIP54) (90 kDa SH3 protein interacting with Nck) (AF3p21) (Dia-interacting protein 1) (DIP-1) (Diaphanous protein-interacting protein) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-interacting protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000213672 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NZQ3 |
| Gene Card | NCKIPSD |
| Uniprot ID | Q9NZQ3 |
| Pfam | PF00018; PF09431 |
| In ASD | no |
| Allosteric Prediction | no (-0.613357061) |
| Ortholog in Animals | Alpaca_ NCKIPSD ( ortholog_one2one ) Dog_ NCKIPSD ( ortholog_one2one ) GuineaPig_ NCKIPSD ( ortholog_one2one ) Macaque_ NCKIPSD ( ortholog_one2one ) Mouse_ Nckipsd ( ortholog_one2one ) Pig_ NCKIPSD ( ortholog_one2one ) Rat_ Nckipsd ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest expression in heart, brain, skeletal muscle, kidney and liver. Lower levels in placenta, lung, small intestine and leukocytes. Weak expression in colon, thymus and spleen. {ECO:0000269|PubMed:10619843}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003390(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6DEC (X-ray 4.60A ) 6DED (X-ray 2.20A ) 6DEE (X-ray 3.04A ) |
| DBSNP | rs6785620 rs17855516 |
| Subcellular location [CC] | Nucleus. Note=Colocalizes with DRF1 at membrane ruffles, and with Nck at Z-disks in mature cardiac myocytes. |
| Mouse PG classification | NA |
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