Gene Information
Gene NameSIRPB2
OrganismHomo sapiens (Human)
Gene Length342
Protein NamesSignal-regulatory protein beta-2 (SIRP-beta-2) (Protein tyrosine phosphatase non-receptor type substrate 1-like 3) (Protein tyrosine phosphatase non-receptor type substrate protein)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000196209 )
Evolutionary StageMammalia
AlphaFoldDBQ5JXA9
Gene CardSIRPB2
Uniprot IDQ5JXA9
PfamPF07686
In ASDno
Allosteric Predictionno (-1.570801437)
Ortholog in AnimalsAlpaca_ SIRPB2 ( ortholog_one2one )
Dog_ NSFL1C ( ortholog_one2one )
Macaque_ SIRPB2 ( ortholog_one2one )
Pig_ SIRPB2 ( ortholog_one2one )
Rabbit_ SIRPB2 ( ortholog_one2one )
OhnologsNA
ParalogsSIRPA, SIRPD, SIRPB1, SIRPG
Tissuewhole.blood
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs6033876  rs6042507  rs8119290 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass type I membrane protein {ECO:0000305}.
Mouse PG classificationNA
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