| Gene Information | |
|---|---|
| Gene Name | WRNIP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 665 |
| Protein Names | ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000124535 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96S55 |
| Gene Card | WRNIP1 |
| Uniprot ID | Q96S55 |
| Pfam | PF00004; PF16193; PF12002; PF18279 |
| In ASD | no |
| Allosteric Prediction | no (-0.371614031) |
| Ortholog in Animals | Alpaca_ WRNIP1 ( ortholog_one2one ) Dog_ WRNIP1 ( ortholog_one2one ) GuineaPig_ WRNIP1 ( ortholog_one2one ) Macaque_ WRNIP1 ( ortholog_one2one ) Mouse_ Wrnip1 ( ortholog_one2one ) Pig_ WRNIP1 ( ortholog_one2one ) Rat_ Wrnip1 ( ortholog_one2one ) Rabbit_ WRNIP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:11301316}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3VHS (X-ray 1.90A ) 3VHT (X-ray 2.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:18842586}. Cytoplasm {ECO:0000269|PubMed:29053956}. Note=Colocalizes with WRN in granular structures in the nucleus. {ECO:0000269|PubMed:18842586, ECO:0000269|PubMed:29053956}. |
| Mouse PG classification | NA |
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