| Gene Information | |
|---|---|
| Gene Name | SMOH |
| Organism | Homo sapiens (Human) |
| Gene Length | 787 |
| Protein Names | Smoothened homolog (SMO) (Protein Gx) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q99835 |
| Gene Card | SMO |
| Uniprot ID | Q99835 |
| Pfam | PF01534; PF01392 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4JKV (X-ray 2.45A ) 4N4W (X-ray 2.80A ) 4O9R (X-ray 3.20A ) 4QIM (X-ray 2.61A ) 4QIN (X-ray 2.60A ) 5L7D (X-ray 3.20A ) 5L7I (X-ray 3.30A ) 5V56 (X-ray 2.90A ) 5V57 (X-ray 3.00A ) 6OT0 (EM 3.90A ) 6XBJ (EM 3.88A ) 6XBK (EM 3.24A ) 6XBL (EM 3.90A ) 6XBM (EM 3.15A ) 7ZI0 (X-ray 3.00A ) |
| DBSNP | rs879255280 rs17710891 rs121918347 rs121918348 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:22072986}; Multi-pass membrane protein {ECO:0000269|PubMed:22072986}. Cell projection, cilium {ECO:0000269|PubMed:22072986}. |
| Mouse PG classification | NA |
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