| Gene Information | |
|---|---|
| Gene Name | THNSL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 484 |
| Protein Names | Threonine synthase-like 2 (TSH2) (EC 4.2.3.-) (Secreted osteoclastogenic factor of activated T-cells) (SOFAT) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000144115 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q86YJ6 |
| Gene Card | THNSL2 |
| Uniprot ID | Q86YJ6 |
| Pfam | PF00291; PF14821 |
| In ASD | no |
| Allosteric Prediction | no (-0.649625017) |
| Ortholog in Animals | Alpaca_ THNSL2 ( ortholog_one2one ) Dog_ THNSL2 ( ortholog_one2one ) GuineaPig_ THNSL2 ( ortholog_one2one ) Macaque_ THNSL2 ( ortholog_one2one ) Mouse_ Thnsl2 ( ortholog_one2one ) Pig_ THNSL2 ( ortholog_one2one ) Rat_ Thnsl2 ( ortholog_one2one ) Rabbit_ THNSL2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | THNSL1, SDSL, CBS, SDS, SRR |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4129190 rs35541720 rs34136143 rs17855905 |
| Subcellular location [CC] | [Isoform SOFAT]: Secreted. Note=Secreted by activated T-cells via a calcineurin-independent pathway. |
| Mouse PG classification | NA |
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