| Gene Information | |
|---|---|
| Gene Name | MIF |
| Organism | Homo sapiens (Human) |
| Gene Length | 560 |
| Protein Names | Muellerian-inhibiting factor (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance) (MIS) |
| Target Name | macrophage migration inhibitory factor |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000240972 ) 3 ( ENSG00000276701 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P03971 |
| Gene Card | AMH |
| Uniprot ID | P03971 |
| Pfam | PF04709; PF00019 |
| In ASD | no |
| Allosteric Prediction | yes (0.924229754) |
| Ortholog in Animals | Alpaca_ MIF ( ortholog_one2one ) Dog_ MIF ( ortholog_one2one ) GuineaPig_ MIF ( ortholog_one2one ) Mouse_ Mif ( ortholog_one2one ) Pig_ MIF ( ortholog_one2one ) Rat_ AABR07064983.2 ( ortholog_one2many ) Rat_ AABR07061532.1 ( ortholog_one2many ) Rat_ AABR07030647.1 ( ortholog_one2many ) Rat_ AABR07016805.1 ( ortholog_one2many ) Rat_ Mif ( ortholog_one2many ) Rat_ AC127887.1 ( ortholog_one2many ) Rabbit_ MIF ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DDT, DDTL |
| Tissue | NA |
| Tissue Specificity | In ovaries, AMH is detected in granulosa cells of early growing follicles. {ECO:0000269|PubMed:14742691}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7L0J (X-ray 2.60A ) |
| DBSNP | rs149082963 rs10407022 rs569914235 rs371874189 rs200523942 rs777003373 rs140765565 rs1358787117 rs138571039 rs10417628 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:2974034, ECO:0000269|PubMed:3754790}. |
| Mouse PG classification | NA |
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