| Gene Information | |
|---|---|
| Gene Name | MICU1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 476 |
| Protein Names | Calcium uptake protein 1, mitochondrial (Atopy-related autoantigen CALC) (ara CALC) (Calcium-binding atopy-related autoantigen 1) (allergen Hom s 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000107745 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BPX6 |
| Gene Card | MICU1 |
| Uniprot ID | Q9BPX6 |
| Pfam | PF13202; PF13833 |
| In ASD | no |
| Allosteric Prediction | no (-1.000310297) |
| Ortholog in Animals | Alpaca_ MICU1 ( ortholog_one2one ) Dog_ MICU1 ( ortholog_one2one ) GuineaPig_ MICU1 ( ortholog_one2one ) Macaque_ MICU1 ( ortholog_one2one ) Mouse_ Micu1 ( ortholog_one2one ) Pig_ MICU1 ( ortholog_one2one ) Rat_ Micu1 ( ortholog_one2one ) Rabbit_ MICU1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MICU2, MICU3 |
| Tissue | NA |
| Tissue Specificity | Expressed in epithelial cell lines. Strongly expressed in epidermal keratinocytes and dermal endothelial cells. {ECO:0000269|PubMed:16002733, ECO:0000269|PubMed:9806765}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4NSC (X-ray 3.20A ) 4NSD (X-ray 2.70A ) 6K7Y (EM 3.60A ) 6LB7 (X-ray 2.10A ) 6LB8 (X-ray 3.28A ) 6LE5 (X-ray 3.10A ) 6WDN (EM 3.20A ) 6WDO (EM 3.60A ) 6XJV (EM 4.17A ) 6XJX (EM 4.60A ) 6XQN (EM 3.30A ) 6XQO (EM 3.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:20693986, ECO:0000269|PubMed:24332854, ECO:0000269|PubMed:26387864, ECO:0000269|PubMed:26774479, ECO:0000269|PubMed:27099988, ECO:0000305|PubMed:24231807}; Single-pass membrane protein {ECO:0000255}. Mitochondrion intermembrane space {ECO:0000269|PubMed:23747253, ECO:0000269|PubMed:24560927, ECO:0000269|PubMed:26387864}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |